The O'Donnell Lab

Laboratory of DNA Replication

Read a summary of The Laboratory of DNA Replication's research.


Read about the discovery of the first protein to encircle DNA and the internal workings of the fastest polymerase known in the world.

Prokaryotic Story

See the very first replisome to be imaged at molecular resolution, and also derived from a eukaryotic cell.

Eukaryotic Story